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F7DIEBM - Evidence-based Medicine

Kód Zakončení Kredity Rozsah Jazyk výuky
F7DIEBM ZK 20P+8C anglicky
Garant předmětu:
Ilya Ivlev
Přednášející:
Gleb Donin, Ilya Ivlev
Cvičící:
Gleb Donin, Ilya Ivlev, Vojtěch Kamenský
Předmět zajišťuje:
katedra biomedicínské techniky
Anotace:

This course introduces fundamentals of evidence-based medicine and its methods. Students will learn (1) modern approaches to clinical evidence synthesis, (2) limitations, use, and assessment of the body of evidence and development of clinical guidelines, conduct meta-analysis (RevMan and R), evaluate quality of evidence (GRADE).

Požadavky:

In the case of foreign lecturers, there will be a weeklong block of intensive contact education for the number of students at least five. If the number of students is less than five, the course will be self-study with consultations using VoIP (e.g. Skype) and a contact 1-or 2-day seminar. The contact seminar will take place at the FBMI or at the home institution of a foreign lecturer. The subjects are concluded by an oral examination. The student must elaborate a paper on a given topic together with the exam in case of the controlled self-study.

Two laboratory exercises are required for admission to the exam (attested by a protocol signed by the student, the tutor and the supervisor of the course).

The protocols will be archived in the Department for Doctoral Studies.

Osnova přednášek:

Osnova přednášek:

1. Introduction to evidence-based medicine, theory of knowledge, and Key Questions

2. Source of evidence, diagnostic and prognostic studies, harm

3. Evidence search, methods, sources, approaches related to the key questions

4. Risk of bias in clinical studies

5. Critical appraisal of diagnostic and prognostic studies with various design

6. Critical appraisal of efficacy and harm studies; and systematic review and meta-analyses

7. Evidence synthesis and comparative effectiveness: methods and steps for systematic reviews, interpretation

8. Evidence synthesis and comparative effectiveness: meta-analyses, approaches and models, modern tools, interpretation

9. Clinical guidelines, strength of evidence, interpretation, use, implementation, and assessment

10. Use of software to support systematic reviews, conduct meta-analysis, and present clinical guidelines

Osnova cvičení:

Cvičení (bloková forma výuky po 4 vyučovacích hodinách):

1. Formulating Key Questions and matching study design, search for evidence, data abstraction, source for bias, practice risk for bias assessment, evidence synthesis

2. Explore differences among various statistical models for meta-analysis, practice conducting meta-analyses in RevMan and R. Assess the methodological quality of systematic reviews in overviews of reviews of healthcare interventions.

Cíle studia:

This course introduces fundamentals of evidence-based medicine and its methods. Students will learn (1) modern approaches to clinical evidence synthesis, (2) limitations, use, and assessment of the body of evidence and development of clinical guidelines, conduct meta-analysis (RevMan and R), evaluate quality of evidence (GRADE).

Studijní materiály:

Povinná:

[1] Guyatt G, Rennie D, O. Meade M, Cook D. Users’ Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice. 3rd ed. McGraw-Hill Education; 2015. 736 p. (or newer)

[2] Nelson HD. Systematic Reviews to Answer Health Care Questions. 1st ed. LWW; 2014. 240 p. (or newer)

Doporučená:

[1] Asche, C. Applying Comparative Effectiveness Data to Medical Decision Making A Practical Guide. Cham: Springer International Publishing: Imprint: Adis. 2016.

Poznámka:

Modul C

Předmět je součástí následujících studijních plánů:
Materiály ke stažení:

Přednášky: 
PřílohaVelikost
PDF icon Evidence based medicine - lectures1.1 MB

Cvičení: