F7ABBBLG - Biology

Basic information about the cellular level of organisms - from acellular through prokaryotic to eukaryotic. The viruses. Prokaryotic cells. Bacteria. Bacterial diseases and their control. Eukaryotic cells. Plant and animal cell structure and function. Structure and conformation of biopolymers (nucleid acids and proteins). The nucleus, plastids, mitochondria. Cytoplasm. Endomembrane system: endoplasmic reticulum, the Golgi apparatus, lysosomes, vacuoles. Semiautonomous organelles: mitochondria, sites of respiration and chloroplasts, sites of photosynthesis. The origin of eukaryotes: endosymbiotic hypothesis. Ribosomes. The cytoskeleton: microtubules, microfilaments. The cell cycle: mitotic (M) phase and interphase (G1, S and G2 phases). The division of cell nucleus - amitosis, mitosis, phases of mitosis, the mitotic spindle; meiosis. The cell division - cytokinesis. Cell differentiation. Cell death. Apoptosis and necrosis. Mendelian and modern genetics: structure, function and inheritance of genes. Includes the chemistry and structure of chromatin and chromosomes. Animal tissue histology. Animal cells and tissues. Human genetics. Chromosomal aberrations, genetic disorders and diseases. Genetic engineering. GMO organisms.

Assessment: Obligatory and active attendance at all tutorials. Absences are acceptable for serious reasons only and must be apologized and recompensed. Student has to come in time. For each lab session working out a report in corresponding quality.

Examination: class ticket, successful mastery of written work, oral exam

Basic information about the cellular level of organisms - from acellular through prokaryotic to eukaryotic. The viruses. Prokaryotic cells. Bacteria. Bacterial diseases and their control. Eukaryotic cells. Plant and animal cell structure and function. The nucleus, plastids, mitochondria. Cytoplasm. Endomembrane system: endoplasmic reticulum, the Golgi apparatus, lysosomes, microbodies (glyoxysomes, peroxisomes), vacuoles. Semiautonomous organelles: mitochondria, sites of respiration and chloroplasts, sites of photosynthesis. The origin of eukaryotes: endosymbiotic hypothesis. Ribosomes. The cytoskeleton: microtubules, microfilaments. The cell cycle: mitotic (M) phase and interphase (G1, S and G2 phases). The division of cell nucleus - amitosis, mitosis, phases of mitosis, the mitotic spindle; meiosis. The cell division - cytokinesis. Cell differentiation. Cell death. Apoptosis and necrosis. Mendelian and modern genetics: structure, function and inheritance of genes. Includes the chemistry and structure of chromatin and chromosomes. Plant anatomy and histology. Types of plant cells and tissues. Tissue systems: meristems, epidermal, water-conducting and ground tissues, their structure and functions. Animal tissue histology. Animal cells and tissues. Human genetics. Chromosomal aberrations, genetic disorders and diseases. Genetic engineering. GMO organisms. Gene therapy.

1. Microscopy. Microscopic Methods.

2. The preparation of the microscopic sample.

3. Prokaryotic cell microscopy.

4. Eukaryotic cell microscopy.

5. Cell Organelles microscopy.

6. Cell Organelles microscopy.

7. Cell division. Mitosis.

8. Cell plasmolysis.

9. Plant anatomy and organology.

10. Animal tissues.

11. Genetics - exercises.

12. Genetics - exercises.

13. Molecular biology.

Basic information about the cellular level of organisms - from acellular through prokaryotic to eukaryotic. The viruses. Prokaryotic cells. Bacteria. Bacterial diseases and their control. Eukaryotic cells. Plant and animal cell structure and function. Structure and conformation of biopolymers (nucleic acids and proteins). The nucleus, plastids, mitochondria. Cytoplasm. Endomembrane system: endoplasmic reticulum, the Golgi apparatus, lysosomes, microbodies (glyoxysomes, peroxisomes), vacuoles. Semiautonomous organelles: mitochondria, sites of respiration and chloroplasts, sites of photosynthesis. The origin of eukaryotes: endosymbiotic hypothesis. Ribosomes. The cytoskeleton: microtubules, microfilaments. The cell cycle: mitotic (M) phase and interphase (G1, S and G2 phases). The division of cell nucleus - amitosis, mitosis, phases of mitosis, the mitotic spindle; meiosis. The cell division - cytokinesis. Cell differentiation. Cell death. Apoptosis and necrosis. Mendelian and modern genetics: structure, function and inheritance of genes. Includes the chemistry and structure of chromatin and chromosomes. Plant anatomy and histology. Types of plant cells and tissues. Tissue systems: meristems, epidermal, water-conducting and ground tissues, their structure and functions. Animal tissue histology. Animal cells and tissues. Human genetics. Chromosomal aberrations, genetic disorders and diseases. Genetic engineering. GMO organisms. Gene therapy.

Povinná literatura

[1] Alberts B., Heald Rebecca, Bray D., Lewis J. a kol.: Molecular Biology of the Cell (7th ed.) Garland Science NY 2022, USA

[2] Solomon Eldra Pearl, Berg Linda R., Martin Diana W. Biology. 2018. Nakladatel: Cengage Learning, Inc USA

[3] Thomas D. Pollard and William C. Earnshaw: Cell Biology, Updated Edition, 2004, Elsevier

[4]Campbell, Neil Biology: A Global Approach, Global Edition (anglicky) 2020 nakladatel: Pearson Education Limited

Doporučená literatura

[1] VYMĚTALOVÁ, Veronika. Biologie pro biomedicínské inženýrství. 3. přepracované vydání. V Praze: České vysoké učení technické v Praze, Česká technika-nakladatelství ČVUT, 2019. ISBN 978-80-01-06533-4

[2] VYMĚTALOVÁ V.: Biologie pro biomedicínské inženýrství - laboratorní cvičení, skripta ČVUT 2021, ISBN 978-80-01-06789-5

[3] Reischig, J.; Korabečná, M.; Kufner, P.; Hatina, J.: Obecná biologie. Praktická cvičení. Praha, Karolinum 2000,

[4] Campbell N.A. , Reece J.B.: Biologie. Computer Press, Brno 2006.

• Prospectus - bakalářský (!)
• Biomedical Technology (compulsory course)
• Biomedical Technology (compulsory course)