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F7ADIFP - Selected Chapters from Human Physiology and Pathophysiology

Code Completion Credits Range Language
F7ADIFP ZK 28P English
Leoš Navrátil, Ivan Dylevský (guarantor)
Department of Health Care Disciplines and Population Protection

The course provides a brief overview of the physiology, pathology and pathophysiology of organ systems. Attention is focused on disorders of organ functions, leading to the development of specific pathophysiological syndromes.


In addition to the exam, the student is required to prepare a written study on a given topic.

Syllabus of lectures:

Syllabus of lectures:

[1]General causes of diseases, etiology and pathogenesis, syndrome / symptom. External factors of disease? physical, chemical and biological pathogenic factors.

[2]Cell / tissue / organ, regulation of proliferation, differentiation and cell death (necrosis vs. apoptosis), tissue damage, inflammation, local and systemic manifestations, cytokines and chemokines, general manifestations of diseases (fever, pain), regeneration vs. repair, wound healing and its disorders.

[3]Basics of genetics, genetic variability, diseases due to chromosome aberrations, monogenic vs. complex (civilization) diseases.

[4]Cell cycle control, tumor cell transformation, carcinogens, metastasis, tumor-organism interactions, sporadic vs. familial forms.

[5]Pathophysiology of the respiratory system.

[6]Pathophysiology of blood.

[7]Pathophysiology of the circulatory system.

[8]Pathophysiology of the excretory system.

[9]Homeostasis. Disorders of homeostasis.

[10]Pathophysiology of the digestive system.

[11]Pathophysiology of internal secretion.

[12]Disorders of metabolism.

[13]Pathophysiology of allergic and autoimmune diseases.

[14]Eating disorders. Thermodynamics of living systems, principles and classification of biological transports.

Syllabus of tutorials:
Study Objective:
Study materials:
The course is a part of the following study plans: