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17ADBBIOC - Bio system man

Code Completion Credits Range Language
17ADBBIOC ZK 5 2P English
Lecturer:
Tutor:
Supervisor:
Department of Biomedical Technology
Synopsis:

Basic concepts of systemic approach to the human organism. Functional organization of living systems. Integrated functions and importance of systems interesting biomedical technicians and engineers. Principles of experimental and investigative methods used in physiology and medicine. Examples of modern technological contributions to medicine.

Requirements:

Assimilation of lectures based on pre-distributed documents + elaboration of a written study at a given theme. Participation in two laboratory exercises and elaboration of a protocol incorporated into their doctoral file.

If the number of students is less than 5, a mode of supervised self-learning with regular consultation may be considered. The examination will be in oral or written forms.

Syllabus of lectures:

1 SYSTEMIC APPROACH TO THE HUMAN ORGANISM

Functional organization of living organisms. What is life? Thermodynamics

of living systems; evolutionary and ecological aspects.

Biological transports: principles and classification. Bioenergetics.

From cell to organism: functional hierarchy and coordination in the human

organism. Experimental approach and modelling.

Adaptation: physical and chemical parameters compatible with survival,

concept of homeostasis.

2 EXCHANGES – BASIS OF LIFE

Blood circulation and gas exchanges. Functional interrelationships and

regulatory mechanisms. Ischemia, hypoxia, oxidative stress.Technological

supports.

Assimilation and excretion.

Digestive motility: investigation (special lecture: from idea to clinical use).

Renal exchanges: transport of solutes and water. Hemodialysis.

Information processing: principles of intercellular communication.

Neural signals: origins, coding, propagation, storage, modulation.

Neuro-muscular system: from motor unit to speech.

3 INTEGRATIVE MECHANISMS

Homeostasis of vital parameters.

Adaptation to physical effort.

Behaviour: Introduction into cognitive functions. Man – zoon politicon.

Syllabus of tutorials:

Two experimental sessions (2x4 hours):

1.Cell physiology: osmotic resistance of erythrocytes.

2.Human physiology: energy metabolism, ergometry

Study Objective:

- To revise physiological knowledge from the point of view of engineers.

- To understand principles of investigative methods used in physiology and

medicine.

- To realize the importance of integrative approach to functional systems with

respect to application in technological development.

- To stimulate search for open medical problems and their solutions.

Study materials:

Obligatory:

[1] P. Kucera: Documents and outlines distributed in advance to lectures.

[2] Lauralee Sherwood: Human physiology, From cells to Systems, 9th

edition, 2016. Can be downloaded free of charge (Academia.edu)

Recommended:

[3] W. Textbook Boron, E.L. Boulpaep of Medical Physiology, 3d edition,

Elsevier 2016.

[4] A.C. Guyton, J.E. Hall Textbook of Medical Physiology, 13th edition,

Elsevier 2015

Note:
The course is a part of the following study plans:
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