17ABBFCH - Physical Chemistry

Mixtures of compounds. Vapour and vaporisation. Electrodes. Electrochemical potential, electrodes. Referent and measuring electrodes, ECG, EEG and EMG electrodes. Redox potential. Inert electrodes. Membranes. Osmotic pressure. Ion-sensitive electrodes. Acidity. Measurement of pH, pO2, pCO2. Electrolysis and its application. Corrosion and protection of implants. Other amalytical methods based on principles of physical chemistry.

Conditions of assesment :

Due to COVID-19 pandemic the tutorials and lectures have been fully transferred to on-line form.

In order to obtain assesment under this situation, you need to fulfill the following:

! in time handling of homework from tutorials in MS Teams- please learn how to add homework and handle it in the assignements section in MS Teams. People who repeteadly fail to handle the homework on time will not be allowed to obtain the assesment.

the attentance to online sessions of tutiorials ín MS Teams is obligatory, (absence allowed in special cases following written excuse and the replacement will be agreed on individually)

passing two credit tests from the topics taught on tutorials (each of the tests must be written for at least 60%).

The subject ends with an exam, which is graded according to the ECTS scale, and to pass the exam, the test must be evaluated at least at 50 %. Your independent work, homework and activity on the tutorials is also part of the classification.

1. Objectives of the subject. Basic principles of physical chemistry. Physical and chemical properties of compounds. Basic calculations.

2. Mixtures of compounds-gases.

3. Mixtures of compounds-solid and liquid compounds.

4. Evaporation, saturated vapour. Humidifiers and vaporizers of anaesthetic compounds.

5. Electrochemical potential, electrodes. Nernst equation. Electrodes of the first type. Electrochemical cell and half-cell. Application in biomedical engineering.

6. Electrodes of the second type. Solubility product. Reference electrodes. ECG, EEG and EMG electrodes.

7. Redox potential. Inert electrodes. Calculation of redox potential. Application in BME.

8. Membranes-types, properties and application. Osmotic pressure. Ion-sensitive electrodes. Acidity of solutions, pH. Measurement of pH.

9. Stability of materials and corrosion. Anodic reactions. Corrosive speed.

10. Electrolysis, conductivity of solutions and its measurement. Other methods for analysis of solutions and gases. Applications in BME.

11. Optical absorption. Spectrophotometry, etc. Application in BME.

12. Fluorescence a phosphorescence. Sensors for pH, pO2, pCO2 and SO2 measurement based on optical principles.

13. Advanced analytical methods and equipment. Mass spectroscopy, nuclear magnetic resonance, atomic absorption spectrophotometry, etc.

14. Thermodynamics-basic principles and calculations.

1. Basic calculations in physical chemistry. Calculations with gases. Calculations from chemical equations.

2. Basic calculations in physical chemistry. Calculations from chemical equations.

3.Basic calculations in physical chemistry

4. Acidity, basicity, the pH of solutions and buffers

5. Acidity, basicity, the pH of solutions and buffers

6. TEST 1

7. correction of midterm test 1

8. Calculations in electrochemistry I.

9. Calculations in electrochemistry II

10. Calculations from the equation of the state

11. solubility product, mean activity coefficient

12. thermodynamics

13. TEST 2

14.

The aim of the subject is to give students the basic principles of the physical chemistry that are essential for design and work of the medical equipment, in clinical trials and in clinical practice. Application of these principles in the practice is explained.

[1] Atkins, P., Paula, J.: Atkins' Physical Chemistry. (Eighth Edition). Oxford University Press, Oxford, 2006.

[2] Raff, M. L.: Principles of Physical Chemistry. (Paarts 1 and 2). Prentice Hall, Upper Saddle River, 2001.

• Biomedical Technician - full time study in English (compulsory course)