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17ABBBUI - Biological Effects of Ionizing Radiation

Code Completion Credits Range Language
17ABBBUI KZ 2 2+0
Lecturer:
Jana Hudzietzová
Tutor:
Jana Hudzietzová
Supervisor:
Department of Health Care Disciplines and Population Protection
Synopsis:

The lectures will give an overview of basic radiation biology. Students will become familiar with the biological effects of ionizing radiation: the physical and chemical processes by which radiation causes damage to the biological material; mechanisms of radiation action on the DNA and other constituents of the cell; types of damage and their repair; subcellular and cellular sensitivity and radiation response; physical, chemical and biological modifiers of radiation action; theories and models of cellular survival; and radiation biology of normal and neoplastic tissues.

Requirements:

classified credit:

demonstration of the knowledge mastered by a written test, 80 % success rate.

Oral examination on the basis of the decision field supervisor.

note: the interval between testing and the outcome in due time or the corrective terms must be at least seven days.

Syllabus of lectures:

1st Week - Construction of a cell. DNA. Cell cycle.

2nd week - DNA repair processes. Chromosomal aberrations.

3rd week - Radiobiology definitions and units of physical processes occurring in the absorption of radiation, absorption mechanisms, methods of radiation detection.

4th Week - Dosimetry.

5th Week - Effects of ionizing radiation on the level of cells and tissues.

6th Week - Biodozimetrie.

7th week - The clinical radiobiology. Effects of radiation on the embryo and fetus, hereditary effects, late effects of ionizing radiation.

8th Week - Acute and chronic radiation sickness.

9th Week - Radiomodulátory. Interaction of radiation with chemicals.

10th Week - Introduction to radiation protection.

11th Week - Nuclear Energy.

12th week - Terrorism, the possibility of misuse of nuclear weapons

13th Week - Introduction to radiotherapy.

14th week - Free topic

Note - The order of presentations may change, students will be informed.

Syllabus of tutorials:

N/A

Study Objective:

12th week - terrorism, the possibility of misuse of nuclear weaponsf cell, tissue, full body. Fundamentals of pathology and diagnosis of radiation sickness, pre-medical assistance.Basics of radiation protection. Non-ionizing radiation.

Study materials:

1.HALL, Eric J. a Amato J. GIACCIA. Radiobiology for the radiologist. 7th ed. Philadelphia: Wolters Kluwer :Lippincott Williams & Wilkins, 2012.

2.STEEL, G. Gordon., ed. Basic clinical radiobiology. 3rd ed. London: Arnold, 2002.

Note:
The course is a part of the following study plans:
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