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17ABBBCH - Biochemistry

Code Completion Credits Range Language
17ABBBCH KZ 2 1+1
Enrollement in the course requires an successful completion of the following courses:
Biology (17ABBBLG)
Chemistry (17PBBCHM)
Lenka Strnadová (guarantor)
Lenka Strnadová (guarantor)
Department of Biomedical Technology

This subject introduces basics of biochemistry, namely the structure and properties of biochemical compounds, principles of metabolism and energy transformations in living organisms.


Conditions of credit:

Obligatory and active attendance at all tutorials. Absences are acceptable for serious reasons only and must be apologized and recompensed. Student has to come in time.

For the attendance at each tutorials, student has to pass an entrance test at least for 50 %. In the other way, he has to recompense the session with the test on an other date. An entrance test could contain the topics from the actual lecture and from the base and instructions for the labo session. Student can gain 32 points from the entrance tests (6 tests, 6 points), which will be part of the grading.

At the end of the semester student has to pass a written final credit test, containing the discussed topics and lab sessions. The final credit test must be written at least at 50%. According to the Dean's directive, student has one attempt for writing the final credit test. The final grade is created by the sum of both the points from the entrance tests and from the final test. and in evaluated according to the ECTS scale.

Syllabus of lectures:

1. Introduction to biochemistry

2. Nucleic acids

3. Amino-acids, peptides and proteins

4. Carbohydrates

5. Lipids and biomembranes

6. Enzymes

7. Principles of metabolism and important biochemical pathways

Syllabus of tutorials:

1. Cell, organic molecules, pH, non-covalent interactions

2. Properties of amino acids, peptide bond, titration of amino acids and TLC

3. Structure of saccharides and their clinical estimation.

4. Properties of lipids, lipid particles. Review presentation - 1st part:

5. Enzyme classes, enzyme kinetics. Review presentation - 2nd part

6. Glycolysis, citrate cycle, respiration chain. Review presentation - 3rd part

Study Objective:

The goal of study is to understand the significance of biochemical compounds in living organisms, and to deduce their properties by the knowledge of their structure. After passing the course, student should be well versed in biochemical problems either of clinical diagnostics either of daily life. Further aim of this subject is to get work with scientific publications, search for biochemical information and to present obtained knowledge to other students.

Study materials:

[1] Murray, R.K., et al.: Harper´s illustrated biochemistry. Mc Graw Hill Medical, New York 2009.

[2] Nelson, D.L., Cox, M.M.: Lehninger principles of biochemistry, WH Freeman, New York 2008.

[3] Voet, D., Voet, J.G.: Biochemistry. Wiley, Hoboken 2011.

The course is a part of the following study plans: